FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Nectin 1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human PVRL1. AA range:81-130
特异性
Nectin 1 Polyclonal Antibody detects endogenous levels of Nectin 1 protein.
基因名称
PVRL1
蛋白名称
Poliovirus receptor-related protein 1
别名
PVRL1;HVEC;PRR1;Poliovirus receptor-related protein 1;Herpes virus entry mediator C;Herpesvirus entry mediator C;HveC;Herpesvirus Ig-like receptor;HIgR;Nectin-1;CD111
Organism-1
Human
基因ID-1
5818
SwissProt-1
Q15223
Organism-2
Mouse
基因ID-2
58235
SwissProt-2
Q9JKF6
背景
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009],
细胞定位
[Isoform Alpha]: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, presynaptic cell membrane .; [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; [Isoform Gamma]: Secreted.
