FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CD98
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
69kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human SLC3A2. AA range:491-540
特异性
CD98 Polyclonal Antibody detects endogenous levels of CD98 protein.
基因名称
SLC3A2
蛋白名称
4F2 cell-surface antigen heavy chain
别名
SLC3A2;MDU1;4F2 cell-surface antigen heavy chain;4F2hc;4F2 heavy chain antigen;Lymphocyte activation antigen 4F2 large subunit;CD98
Organism-1
Human
基因ID-1
6520
SwissProt-1
P08195
Organism-2
Mouse
基因ID-2
17254
SwissProt-2
P10852
Organism-3
Rat
基因ID-3
50567
SwissProt-3
Q794F9
背景
This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. [provided by RefSeq, Nov 2010],
细胞定位
Apical cell membrane . Cell membrane ; Single-pass type II membrane protein . Cell junction . Lysosome membrane . Melanosome . Localized at the plasma membrane when associated with SLC7A5/LAT1 or SLC7A8/LAT2 (PubMed:9751058, PubMed:11311135). Localized to the apical membrane of placental syncytiotrophoblastic cells (PubMed:11742812). Recruited to lysosomes by LAPTM4B (PubMed:25998567). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Located selectively at cell-cell adhesion sites (By similarity). Colocalized with SLC7A8/LAT2 at the basolateral membrane of kidney proximal tubules and small intestine epithelia. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells (By similarity). .
