FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LIR-1
反应性
Human
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
72kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human LILRB1. AA range:21-70
特异性
LIR-1 Polyclonal Antibody detects endogenous levels of LIR-1 protein.
基因名称
LILRB1
蛋白名称
Leukocyte immunoglobulin-like receptor subfamily B member 1
别名
LILRB1;ILT2;LIR1;MIR7;Leukocyte immunoglobulin-like receptor subfamily B member 1;LIR-1;Leukocyte immunoglobulin-like receptor 1;CD85 antigen-like family member J;Immunoglobulin-like transcript 2;ILT-2;Monocyte/macrophage immunoglobulin-like receptor 7;MIR-7;CD85j
Organism-1
Human
基因ID-1
10859
SwissProt-1
Q8NHL6
背景
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein .; [Isoform 5]: Secreted .
