- 产品信息
商品描述
靶点-Target
CD53
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD53. AA range:91-140
特异性
CD53 Polyclonal Antibody detects endogenous levels of CD53 protein.
基因名称
CD53
蛋白名称
Leukocyte surface antigen CD53
别名
CD53;MOX44;TSPAN25;Leukocyte surface antigen CD53;Cell surface glycoprotein CD53;Tetraspanin-25;Tspan-25;CD53
Organism-1
Human
基因ID-1
963
SwissProt-1
P19397
Organism-2
Mouse
基因ID-2
12508
SwissProt-2
Q61451
Organism-3
Rat
基因ID-3
24251
SwissProt-3
P24485
背景
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
细胞定位
Cell membrane . Cell junction . Membrane; Multi-pass membrane protein. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes. .





