CD53 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617348

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商品描述
  • 靶点-Target

    CD53

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    24kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human CD53. AA range:91-140

  • 特异性

    CD53 Polyclonal Antibody detects endogenous levels of CD53 protein.

  • 基因名称

    CD53

  • 蛋白名称

    Leukocyte surface antigen CD53

  • 别名

    CD53;MOX44;TSPAN25;Leukocyte surface antigen CD53;Cell surface glycoprotein CD53;Tetraspanin-25;Tspan-25;CD53

  • Organism-1

    Human

  • 基因ID-1

    963

  • SwissProt-1

    P19397

  • Organism-2

    Mouse

  • 基因ID-2

    12508

  • SwissProt-2

    Q61451

  • Organism-3

    Rat

  • 基因ID-3

    24251

  • SwissProt-3

    P24485

  • 背景

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

  • 细胞定位

    Cell membrane . Cell junction . Membrane; Multi-pass membrane protein. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes. .