Integrin α6 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617347
- 产品信息
商品描述
靶点-Target
Integrin α6
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
125kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human ITGA6. AA range:901-950
特异性
Integrin α6 Polyclonal Antibody detects endogenous levels of Integrin α6 protein.
基因名称
ITGA6
蛋白名称
Integrin alpha-6
别名
ITGA6;Integrin alpha-6;CD49 antigen-like family member F;VLA-6;CD49f
Organism-1
Human
基因ID-1
3655
SwissProt-1
P23229
Organism-2
Mouse
SwissProt-2
Q61739
背景
integrin subunit alpha 6(ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor .





