CD42d/GPV Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617344
- 产品信息
商品描述
靶点-Target
CD42d
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,FC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
62kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human GP5. AA range:331-380
特异性
CD42d Polyclonal Antibody detects endogenous levels of CD42d protein.
基因名称
GP5
蛋白名称
Platelet glycoprotein V
别名
GP5;Platelet glycoprotein V;GPV;Glycoprotein 5;CD42d
Organism-1
Human
基因ID-1
2814
SwissProt-1
P40197
Organism-2
Mouse
SwissProt-2
O08742
Organism-3
Rat
基因ID-3
25259
SwissProt-3
O08770
背景
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010],
细胞定位
Membrane; Single-pass type I membrane protein.





