CD42d/GPV Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617344

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商品描述
  • 靶点-Target

    CD42d

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,FC,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    62kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human GP5. AA range:331-380

  • 特异性

    CD42d Polyclonal Antibody detects endogenous levels of CD42d protein.

  • 基因名称

    GP5

  • 蛋白名称

    Platelet glycoprotein V

  • 别名

    GP5;Platelet glycoprotein V;GPV;Glycoprotein 5;CD42d

  • Organism-1

    Human

  • 基因ID-1

    2814

  • SwissProt-1

    P40197

  • Organism-2

    Mouse

  • SwissProt-2

    O08742

  • Organism-3

    Rat

  • 基因ID-3

    25259

  • SwissProt-3

    O08770

  • 背景

    Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010],

  • 细胞定位

    Membrane; Single-pass type I membrane protein.