Integrin αL Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

一键复制产品信息
产品规格:
  • 50μL
  • 100μL
货号:

FAB2617337

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    Integrin αL

  • 反应性

    Human,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    130kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human ITGAL. AA range:171-220

  • 特异性

    Integrin αL Polyclonal Antibody detects endogenous levels of Integrin αL protein.

  • 基因名称

    ITGAL

  • 蛋白名称

    Integrin alpha-L

  • 别名

    ITGAL;CD11A;Integrin alpha-L;CD11 antigen-like family member A;Leukocyte adhesion glycoprotein LFA-1 alpha chain;LFA-1A;Leukocyte function-associated molecule 1 alpha chain;CD11a

  • Organism-1

    Human

  • 基因ID-1

    3683

  • SwissProt-1

    P20701

  • Organism-2

    Mouse

  • SwissProt-2

    P24063

  • 背景

    integrin subunit alpha L(ITGAL) Homo sapiens ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane ; Single-pass type I membrane protein .