FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PSGL-1
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD,110kD(glycosylated)
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELPLG. AA range:1-50
特异性
PSGL-1 Polyclonal Antibody detects endogenous levels of PSGL-1 protein.
基因名称
SELPLG
蛋白名称
P-selectin glycoprotein ligand 1
别名
SELPLG;P-selectin glycoprotein ligand 1;PSGL-1;Selectin P ligand;CD162
Organism-1
Human
基因ID-1
6404
SwissProt-1
Q14242
Organism-2
Mouse
SwissProt-2
Q62170
背景
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011],
细胞定位
Membrane; Single-pass type I membrane protein.
