GABAA Rα1 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617329
- 产品信息
商品描述
靶点-Target
GABAA Rα1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human GABRA1. AA range:61-110
特异性
GABAA Rα1 Polyclonal Antibody detects endogenous levels of GABAA Rα1 protein.
基因名称
GABRA1
蛋白名称
Gamma-aminobutyric acid receptor subunit alpha-1
别名
GABRA1;Gamma-aminobutyric acid receptor subunit alpha-1;GABA;A;receptor subunit alpha-1
Organism-1
Human
基因ID-1
2554
SwissProt-1
P14867
Organism-2
Mouse
基因ID-2
14394
SwissProt-2
P62812
Organism-3
Rat
基因ID-3
29705
SwissProt-3
P62813
背景
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane .





