CD89 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617328

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商品描述
  • 靶点-Target

    CD89

  • 反应性

    Human

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    32kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human FCAR. AA range:31-80

  • 特异性

    CD89 Polyclonal Antibody detects endogenous levels of CD89 protein.

  • 基因名称

    FCAR

  • 蛋白名称

    Immunoglobulin alpha Fc receptor

  • 别名

    FCAR;CD89;Immunoglobulin alpha Fc receptor;IgA Fc receptor;CD89

  • Organism-1

    Human

  • 基因ID-1

    2204

  • SwissProt-1

    P24071

  • 背景

    This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    [Isoform A.1]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.2]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.3]: Cell membrane; Single-pass type I membrane protein.; [Isoform B]: Secreted.; [Isoform B-delta-S2]: Secreted.