- 产品信息
商品描述
靶点-Target
Dkk-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
29kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human DKK1. AA range:181-230
特异性
Dkk-1 Polyclonal Antibody detects endogenous levels of Dkk-1 protein.
基因名称
DKK1
蛋白名称
Dickkopf-related protein 1
别名
DKK1;Dickkopf-related protein 1;Dickkopf-1;Dkk-1;hDkk-1;SK
Organism-1
Human
基因ID-1
22943
SwissProt-1
O94907
Organism-2
Mouse
基因ID-2
13380
SwissProt-2
O54908
背景
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],
细胞定位
Secreted.





