FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
OAS2
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
82kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110
特异性
OAS2 Polyclonal Antibody detects endogenous levels of OAS2 protein.
基因名称
OAS2
蛋白名称
2'-5'-oligoadenylate synthase 2
别名
OAS2;2'-5'-oligoadenylate synthase 2;2-5';oligo;A;synthase 2;2-5A synthase 2;p69 OAS / p71 OAS;p69OAS / p71OAS
Organism-1
Human
基因ID-1
4939
SwissProt-1
P29728
Organism-2
Mouse
基因ID-2
246728
SwissProt-2
E9Q9A9
Organism-3
Rat
基因ID-3
363938
SwissProt-3
Q5MYU0
背景
2'-5'-oligoadenylate synthetase 2(OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Cytoplasm, perinuclear region .
