CD292 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

一键复制产品信息
产品规格:
  • 50μL
  • 100μL
货号:

FAB2617297

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    CD292

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    60kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the N-terminal region of human BMPR1A. AA range:1-50

  • 特异性

    CD292 Polyclonal Antibody detects endogenous levels of CD292 protein.

  • 基因名称

    BMPR1A

  • 蛋白名称

    Bone morphogenetic protein receptor type-1A

  • 别名

    BMPR1A;ACVRLK3;ALK3;Bone morphogenetic protein receptor type-1A;BMP type-1A receptor;BMPR-1A;Activin receptor-like kinase 3;ALK-3;Serine/threonine-protein kinase receptor R5;SKR5;CD292

  • Organism-1

    Human

  • 基因ID-1

    657

  • SwissProt-1

    P36894

  • Organism-2

    Mouse

  • 基因ID-2

    12166

  • SwissProt-2

    P36895

  • Organism-3

    Rat

  • 基因ID-3

    81507

  • SwissProt-3

    Q78EA7

  • 背景

    The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane ; Single-pass type I membrane protein . Cell surface .