- 产品信息
商品描述
靶点-Target
SPARC
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
34kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human SPARC. AA range:141-190
特异性
SPARC Polyclonal Antibody detects endogenous levels of SPARC protein.
基因名称
SPARC
蛋白名称
SPARC
别名
SPARC;ON;SPARC;Basement-membrane protein 40;BM-40;Osteonectin;ON;Secreted protein acidic and rich in cysteine
Organism-1
Human
基因ID-1
6678
SwissProt-1
P09486
Organism-2
Mouse
基因ID-2
20692
SwissProt-2
P07214
Organism-3
Rat
基因ID-3
24791
SwissProt-3
P16975
背景
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015],
细胞定位
Secreted, extracellular space, extracellular matrix, basement membrane . In or around the basement membrane.





