- 产品信息
商品描述
靶点-Target
IL-1F8
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
19kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL36B. AA range:111-160
特异性
IL-1F8 Polyclonal Antibody detects endogenous levels of IL-1F8 protein.
基因名称
IL36B
蛋白名称
Interleukin-36 beta
别名
IL36B;IL1F8;IL1H2;Interleukin-36 beta;FIL1 eta;Interleukin-1 eta;IL-1 eta;Interleukin-1 family member 8;IL-1F8;Interleukin-1 homolog 2;IL-1H2
Organism-1
Human
基因ID-1
27177
SwissProt-1
Q9NZH7
Organism-2
Mouse
基因ID-2
69677
SwissProt-2
Q9D6Z6
背景
The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .





