FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CRF-RI
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CRHR1. AA range:71-120
特异性
CRF-RI Polyclonal Antibody detects endogenous levels of CRF-RI protein.
基因名称
CRHR1
蛋白名称
Corticotropin-releasing factor receptor 1
别名
CRHR1;CRFR;CRFR1;CRHR;Corticotropin-releasing factor receptor 1;CRF-R-1;CRF-R1;CRFR-1;Corticotropin-releasing hormone receptor 1;CRH-R-1;CRH-R1
Organism-1
Human
基因ID-1
1394
SwissProt-1
P34998
Organism-2
Mouse
基因ID-2
12921
SwissProt-2
P35347
Organism-3
Rat
基因ID-3
58959
SwissProt-3
P35353
背景
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Aug 2016],
细胞定位
Cell membrane; Multi-pass membrane protein. Endosome. Agonist-binding promotes endocytosis.
