FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IL-33
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
31kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human IL33. AA range:121-170
特异性
IL-33 Polyclonal Antibody detects endogenous levels of IL-33 protein.
基因名称
IL33
蛋白名称
Interleukin-33
别名
IL33;C9orf26;IL1F11;NFHEV;Interleukin-33;IL-33;Interleukin-1 family member 11;IL-1F11;Nuclear factor from high endothelial venules;NF-HEV
Organism-1
Human
基因ID-1
90865
SwissProt-1
O95760
Organism-2
Mouse
基因ID-2
77125
SwissProt-2
Q8BVZ5
Organism-3
Rat
基因ID-3
361749
SwissProt-3
Q66H70
背景
The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015],
细胞定位
Nucleus . Chromosome . Cytoplasm . Cytoplasmic vesicle, secretory vesicle . Secreted . Associates with heterochromatin and mitotic chromosomes (PubMed:17185418). The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
