FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DcR1
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human TNFRSF10C. AA range:11-60
特异性
DcR1 Polyclonal Antibody detects endogenous levels of DcR1 protein.
基因名称
TNFRSF10C
蛋白名称
Tumor necrosis factor receptor superfamily member 10C
别名
TNFRSF10C;DCR1;LIT;TRAILR3;TRID;Tumor necrosis factor receptor superfamily member 10C;Antagonist decoy receptor for TRAIL/Apo-2L;Decoy TRAIL receptor without death domainDecoy receptor 1;DcR1;Lymphocyte inhibitor of TRAIL;TNF-related apoptosis-inducing ligand receptor 3;TRAIL receptor 3;TRAIL-R3;TRAIL receptor without an intracellular domain;CD263
Organism-1
Human
基因ID-1
8794
SwissProt-1
O14798
背景
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Lipid-anchor, GPI-anchor.
