- 产品信息
商品描述
靶点-Target
CD239
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
78kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human BCAM. AA range:191-240
特异性
CD239 Polyclonal Antibody detects endogenous levels of CD239 protein.
基因名称
BCAM
蛋白名称
Basal cell adhesion molecule
别名
BCAM;LU;MSK19;Basal cell adhesion molecule;Auberger B antigen;B-CAM cell surface glycoprotein;F8/G253 antigen;Lutheran antigen;Lutheran blood group glycoprotein;CD239
Organism-1
Human
基因ID-1
4059
SwissProt-1
P50895
Organism-2
Mouse
基因ID-2
57278
SwissProt-2
Q9R069
Organism-3
Rat
基因ID-3
78958
SwissProt-3
Q9ESS6
背景
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],
细胞定位
Membrane; Single-pass type I membrane protein.





