Neuropilin Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617238
- 产品信息
商品描述
靶点-Target
Neuropilin
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
100kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human NRP1. AA range:321-370
特异性
Neuropilin Polyclonal Antibody detects endogenous levels of Neuropilin protein.
基因名称
NRP1
蛋白名称
Neuropilin-1
别名
NRP1;NRP;VEGF165R;Neuropilin-1;Vascular endothelial cell growth factor 165 receptor;CD304
Organism-1
Human
基因ID-1
8829
SwissProt-1
O14786
Organism-2
Mouse
基因ID-2
18186
SwissProt-2
P97333
Organism-3
Rat
基因ID-3
246331
SwissProt-3
Q9QWJ9
背景
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
细胞定位
[Isoform 2]: Secreted .; Mitochondrion membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein . Cytoplasm .





