FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SDHB
反应性
Human,Mouse,Rat,Fish
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
31kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human SDHB. AA range:131-180
特异性
SDHB Polyclonal Antibody detects endogenous levels of SDHB protein.
基因名称
SDHB
蛋白名称
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit mitochondrial
别名
SDHB;SDH;SDH1;Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial;Iron-sulfur subunit of complex II;Ip
Organism-1
Human
基因ID-1
6390
SwissProt-1
P21912
Organism-2
Mouse
基因ID-2
67680
SwissProt-2
Q9CQA3
Organism-3
Rat
基因ID-3
298596
SwissProt-3
P21913
背景
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
