ApoA-I Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617225

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商品描述
  • 靶点-Target

    ApoA-I

  • 反应性

    Human,Mouse

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    31kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human APOA1. AA range:81-130

  • 特异性

    ApoA-I Polyclonal Antibody detects endogenous levels of ApoA-I protein.

  • 基因名称

    APOA1

  • 蛋白名称

    Apolipoprotein A-I

  • 别名

    APOA1;Apolipoprotein A-I;Apo-AI;ApoA-I;Apolipoprotein A1

  • Organism-1

    Human

  • 基因ID-1

    335

  • SwissProt-1

    P02647

  • Organism-2

    Mouse

  • 基因ID-2

    11806

  • SwissProt-2

    Q00623

  • 背景

    This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015],

  • 细胞定位

    Secreted.