FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FGF-8
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human FGF8. AA range:141-190
特异性
FGF-8 Polyclonal Antibody detects endogenous levels of FGF-8 protein.
基因名称
FGF8
蛋白名称
Fibroblast growth factor 8
别名
FGF8;AIGF;Fibroblast growth factor 8;FGF-8;Androgen-induced growth factor;AIGF;Heparin-binding growth factor 8;HBGF-8
Organism-1
Human
基因ID-1
2253
SwissProt-1
P55075
Organism-2
Mouse
基因ID-2
14179
SwissProt-2
P37237
背景
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene re
细胞定位
Secreted.
