- 产品信息
商品描述
靶点-Target
EKLF
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KLF1 around the non-acetylation site of Lys274. AA range:231-280
特异性
EKLF Polyclonal Antibody detects endogenous levels of EKLF protein only when acetylation at K274.
基因名称
KLF1
蛋白名称
Krueppel-like factor 1
别名
KLF1;EKLF;Krueppel-like factor 1;Erythroid krueppel-like transcription factor;EKLF
Organism-1
Human
基因ID-1
10661
SwissProt-1
Q13351
Organism-2
Mouse
SwissProt-2
P46099
背景
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009],
细胞定位
Nucleus . Colocalizes with SUMO1 in nuclear speckles. .





