- 产品信息
商品描述
靶点-Target
DRA
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
84kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human DRA.
特异性
DRA Polyclonal Antibody detects endogenous levels of DRA protein.
基因名称
SLC26A3
蛋白名称
Chloride anion exchanger
别名
SLC26A3;DRA;Chloride anion exchanger;Down-regulated in adenoma;Protein DRA;Solute carrier family 26 member 3
Organism-1
Human
基因ID-1
1811
SwissProt-1
P40879
Organism-2
Mouse
基因ID-2
13487
SwissProt-2
Q9WVC8
Organism-3
Rat
基因ID-3
114629
SwissProt-3
Q924C9
背景
The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008],
细胞定位
Apical cell membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . Localized in sperm membranes. Midpiece of sperm tail. Colocalizes with CFTR at the midpiece of sperm tail (By similarity). .





