FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IDH1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
46kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the N-terminal region of human IDH1.
特异性
IDH1 Polyclonal Antibody detects endogenous levels of IDH1 protein.
基因名称
IDH1
蛋白名称
Isocitrate dehydrogenase [NADP] cytoplasmic
别名
IDH1;PICD;Isocitrate dehydrogenase [NADP] cytoplasmic;IDH;Cytosolic NADP-isocitrate dehydrogenase;IDP;NADP;+;-specific ICDH;Oxalosuccinate decarboxylase
Organism-1
Human
基因ID-1
3417
SwissProt-1
O75874
Organism-2
Mouse
基因ID-2
15926
SwissProt-2
O88844
Organism-3
Rat
基因ID-3
24479
SwissProt-3
P41562
背景
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to
细胞定位
Cytoplasm, cytosol . Peroxisome .
