FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MDA-7
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human IL24. AA range:131-180
特异性
MDA-7 Polyclonal Antibody detects endogenous levels of MDA-7 protein.
基因名称
IL24
蛋白名称
Interleukin-24
别名
IL24;MDA7;ST16;Interleukin-24;IL-24;Melanoma differentiation-associated gene 7 protein;MDA-7;Suppression of tumorigenicity 16 protein
Organism-1
Human
基因ID-1
11009
SwissProt-1
Q13007
Organism-2
Mouse
基因ID-2
93672
SwissProt-2
Q925S4
Organism-3
Rat
基因ID-3
170819
SwissProt-3
Q9JI24
背景
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
细胞定位
Secreted .
