CD158b2/j Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617204
- 产品信息
商品描述
靶点-Target
CD158b2/j
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human KIR2DL3/KIR2DS2. AA range:131-180
特异性
CD158b2/j Polyclonal Antibody detects endogenous levels of CD158b2/j protein.
基因名称
KIR2DL3/KIR2DS2
蛋白名称
Killer cell immunoglobulin-like receptor 2DL3/Killer cell immunoglobulin-like receptor 2DS2
别名
KIR2DL3;CD158B2;KIRCL23;NKAT2;Killer cell immunoglobulin-like receptor 2DL3;CD158 antigen-like family member B2;KIR-023GB;Killer inhibitory receptor cl 2-3;MHC class I NK cell receptor;NKAT2a;NKAT2bNatural killer-associated transcript 2;NKAT-2;p58 natural killer cell receptor clone CL-6;p58 NK receptor CL-6;p58.2 MHC class-I-specific NK receptor;CD158b2;KIR2DS2;CD158J;NKAT5;Killer cell immunoglobulin-like receptor 2DS2;
Organism-1
Human
基因ID-1
3804;100132285
SwissProt-1
P43628;P43631
背景
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the
细胞定位
Cell membrane; Single-pass type I membrane protein.





