- 产品信息
商品描述
靶点-Target
Jagged1
反应性
Human,Mouse,Rat
应用
IF,WB,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
140kD
推荐稀释比
IF 1:50-200;WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. AA range:981-1030
特异性
Jagged1 Polyclonal Antibody detects endogenous levels of Jagged1 protein.
基因名称
JAG1
蛋白名称
Protein jagged-1
别名
JAG1;JAGL1;Protein jagged-1;Jagged1;hJ1;CD339
Organism-1
Human
基因ID-1
182
SwissProt-1
P78504
Organism-2
Mouse
基因ID-2
16449
SwissProt-2
Q9QXX0
Organism-3
Rat
基因ID-3
29146
SwissProt-3
Q63722
背景
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008],
细胞定位
Membrane; Single-pass type I membrane protein.





