- 产品信息
商品描述
靶点-Target
CD81
反应性
Human,Mouse,Rat
应用
IF,WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
IF 1:50-200;WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD81. AA range:111-160
特异性
CD81 Polyclonal Antibody detects endogenous levels of CD81 protein.
基因名称
CD81
蛋白名称
CD81 antigen
别名
CD81;TAPA1;TSPAN28;CD81 antigen;26 kDa cell surface protein TAPA-1;Target of the antiproliferative antibody 1;Tetraspanin-28;Tspan-28;CD81
Organism-1
Human
基因ID-1
975
SwissProt-1
P60033
Organism-2
Mouse
基因ID-2
12520
SwissProt-2
P35762
Organism-3
Rat
基因ID-3
25621
SwissProt-3
Q62745
背景
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
细胞定位
Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane ; Multi-pass membrane protein . Associates with CLDN1 and the CLDN1-CD81 complex localizes to the basolateral cell membrane. .





