- 产品信息
商品描述
靶点-Target
NTCP
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human SLC10A1. AA range:281-330
特异性
NTCP Polyclonal Antibody detects endogenous levels of NTCP protein.
基因名称
SLC10A1
蛋白名称
Sodium/bile acid cotransporter
别名
SLC10A1;NTCP;GIG29;Sodium/bile acid cotransporter;Cell growth-inhibiting gene 29 protein;Na;+;/bile acid cotransporter;Na;+;/taurocholate transport protein;Sodium/taurocholate cotransporting polypeptide;Solute carrier family 10 member 1
Organism-1
Human
基因ID-1
6554
SwissProt-1
Q14973
Organism-2
Mouse
SwissProt-2
O08705
背景
The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011],
细胞定位
Cell membrane ; Multi-pass membrane protein.





