- 产品信息
商品描述
靶点-Target
NTE
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
150kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human PNPLA6. AA range:1031-1080
特异性
NTE Polyclonal Antibody detects endogenous levels of NTE protein.
基因名称
PNPLA6
蛋白名称
Neuropathy target esterase
别名
PNPLA6;NTE;Neuropathy target esterase;Patatin-like phospholipase domain-containing protein 6
Organism-1
Human
基因ID-1
10908
SwissProt-1
Q8IY17
Organism-2
Mouse
基因ID-2
50767
SwissProt-2
Q3TRM4
背景
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type III membrane protein .





