Autotaxin Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617160

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商品描述
  • 靶点-Target

    Autotaxin

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    98kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human ENPP2. AA range:401-450

  • 特异性

    Autotaxin Polyclonal Antibody detects endogenous levels of Autotaxin protein.

  • 基因名称

    ENPP2

  • 蛋白名称

    Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

  • 别名

    ENPP2;ATX;PDNP2;Ectonucleotide pyrophosphatase/phosphodiesterase family member 2;E-NPP 2;Autotaxin;Extracellular lysophospholipase D;LysoPLD

  • Organism-1

    Human

  • 基因ID-1

    5168

  • SwissProt-1

    Q13822

  • Organism-2

    Mouse

  • 基因ID-2

    18606

  • SwissProt-2

    Q9R1E6

  • Organism-3

    Rat

  • 基因ID-3

    84050

  • SwissProt-3

    Q64610

  • 背景

    The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008],

  • 细胞定位

    Secreted .