FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ALDH2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
56kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human ALDH2. AA range:41-90
特异性
ALDH2 Polyclonal Antibody detects endogenous levels of ALDH2 protein.
基因名称
ALDH2
蛋白名称
Aldehyde dehydrogenase mitochondrial
别名
ALDH2;ALDM;Aldehyde dehydrogenase, mitochondrial;ALDH class 2;ALDH-E2;ALDHI
Organism-1
Human
基因ID-1
217
SwissProt-1
P05091
Organism-2
Mouse
基因ID-2
11669
SwissProt-2
P47738
Organism-3
Rat
基因ID-3
29539
SwissProt-3
P11884
背景
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform,
细胞定位
Mitochondrion matrix.
