FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EPAS-1
反应性
Human,Mouse,Rat
应用
IF,WB,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
96kD
MW(Observed)
110-120kD
推荐稀释比
IF 1:50-200;WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human EPAS-1 around the non-acetylation site of K385.
特异性
EPAS-1 Polyclonal Antibody detects endogenous levels of EPAS-1 protein.
基因名称
EPAS1 BHLHE73 HIF2A MOP2 PASD2
蛋白名称
Endothelial PAS domain-containing protein 1
别名
EPAS1;BHLHE73;HIF2A;MOP2;PASD2;Endothelial PAS domain-containing protein 1;EPAS-1;Basic-helix-loop-helix-PAS protein MOP2;Class E basic helix-loop-helix protein 73;bHLHe73;HIF-1-alpha-like factor;HLF;Hypoxia-inducible factor 2-alpha;HIF-2-alpha;HIF2-alpha;Member of PAS protein 2;PAS domain-containing protein 2
Organism-1
Human
基因ID-1
2034
SwissProt-1
Q99814
Organism-2
Mouse
基因ID-2
13819
SwissProt-2
P97481
Organism-3
Rat
基因ID-3
29452
SwissProt-3
Q9JHS1
背景
endothelial PAS domain protein 1(EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009],
细胞定位
Nucleus . Nucleus speckle . Colocalizes with HIF3A in the nucleus and speckles. .
