FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IDH3A
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
39kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human IDH3A.
特异性
IDH3A Polyclonal Antibody detects endogenous levels of IDH3A protein.
基因名称
IDH3A
蛋白名称
Isocitrate dehydrogenase [NAD] subunit alpha mitochondrial
别名
IDH3A;Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial;Isocitric dehydrogenase subunit alpha;NAD;+;-specific ICDH subunit alpha
Organism-1
Human
基因ID-1
3419
SwissProt-1
P50213
Organism-2
Mouse
基因ID-2
67834
SwissProt-2
Q9D6R2
Organism-3
Rat
基因ID-3
114096
SwissProt-3
Q99NA5
背景
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion.
