FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GDF-5
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human GDF5. AA range:361-410
特异性
GDF-5 Polyclonal Antibody detects endogenous levels of GDF-5 protein.
基因名称
GDF5
蛋白名称
Growth/differentiation factor 5
别名
GDF5;CDMP1;Growth/differentiation factor 5;GDF-5;Cartilage-derived morphogenetic protein 1;CDMP-1;Radotermin
Organism-1
Human
基因ID-1
8200
SwissProt-1
P43026
Organism-2
Mouse
基因ID-2
14563
SwissProt-2
P43027
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016],
细胞定位
Secreted . Cell membrane .
