- 产品信息
商品描述
靶点-Target
CD159a/c
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human KLRC1/2/3. AA range:101-150
特异性
CD159a/c Polyclonal Antibody detects endogenous levels of CD159a/c protein.
基因名称
KLRC1/KLRC2/KLRC3
蛋白名称
NKG2-A/NKG2-B type II integral membrane protein/NKG2-C type II integral membrane protein/NKG2-E type II integral membrane protein
别名
KLRC1;NKG2A;NKG2-A/NKG2-B type II integral membrane protein;CD159 antigen-like family member A;NK cell receptor A;NKG2-A/B-activating NK receptor;CD159a;KLRC2;NKG2C;NKG2-C type II integral membrane protein;CD159 antigen-like family member C;NK cell receptor C;NKG2-C-activating NK receptor;CD159c;KLRC3;NKG2E;NKG2-E type II integral membrane protein;NK cell receptor E;NKG2-E-activating NK receptor
Organism-1
Human
基因ID-1
3821
SwissProt-1
P26715
背景
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provide
细胞定位
Cell membrane ; Single-pass type II membrane protein .





