FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SIGLEC8
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human SIGLEC8. AA range:81-130
特异性
CD329 Polyclonal Antibody detects endogenous levels of CD329 protein.
基因名称
SIGLEC8
蛋白名称
Sialic acid-binding Ig-like lectin 8
别名
SIGLEC8;SAF2;Sialic acid-binding Ig-like lectin 8;Siglec-8;CDw329;Sialoadhesin family member 2;SAF-2;CD329
Organism-1
Human
基因ID-1
27181
SwissProt-1
Q9NYZ4
背景
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010],
细胞定位
Membrane; Single-pass type I membrane protein.
