- 产品信息
商品描述
靶点-Target
CD161
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human KLRB1. AA range:101-150
特异性
CD161 Polyclonal Antibody detects endogenous levels of CD161 protein.
基因名称
KLRB1
蛋白名称
Killer cell lectin-like receptor subfamily B member 1
别名
KLRB1;CLEC5B;NKRP1A;Killer cell lectin-like receptor subfamily B member 1;C-type lectin domain family 5 member B;HNKR-P1a;NKR-P1A;Natural killer cell surface protein P1A;CD161
Organism-1
Human
基因ID-1
3820
SwissProt-1
Q12918
Organism-2
Mouse
基因ID-2
100043861
SwissProt-2
Q0ZUP1
Organism-3
Rat
基因ID-3
689817
SwissProt-3
Q0ZUP0
背景
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008],
细胞定位
Membrane ; Single-pass type II membrane protein .





