- 产品信息
商品描述
靶点-Target
CD203c
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
100kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human ENPP3. AA range:281-330
特异性
CD203c Polyclonal Antibody detects endogenous levels of CD203c protein.
基因名称
ENPP3
蛋白名称
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
别名
ENPP3;PDNP3;Ectonucleotide pyrophosphatase/phosphodiesterase family member 3;E-NPP 3;Phosphodiesterase I beta;PD-Ibeta;Phosphodiesterase I/nucleotide pyrophosphatase 3;CD203c
Organism-1
Human
基因ID-1
5169
SwissProt-1
O14638
Organism-2
Mouse
基因ID-2
209558
SwissProt-2
Q6DYE8
Organism-3
Rat
基因ID-3
54410
SwissProt-3
P97675
背景
The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Oct 2015],
细胞定位
Cell membrane ; Single-pass type II membrane protein . Apical cell membrane ; Single-pass type II membrane protein . Secreted . Detected at the cell surface of basophils (PubMed:11342463). Detected at the apical plasma membrane of bile duct cells (PubMed:15072822). Located to the apical surface in intestinal and kidney epithelial cells. Secreted in serum, and in lumen of epithelial cells. .





