Siglec-5/14 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617093
- 产品信息
商品描述
靶点-Target
Siglec-5/14
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
44kD or 60kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14 at AA range: 91-140
特异性
Siglec-5/14 Polyclonal Antibody detects endogenous levels of Siglec-5/14 protein.
基因名称
SIGLEC5/SIGLEC14
蛋白名称
Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14
别名
SIGLEC5;CD33L2;OBBP2;Sialic acid-binding Ig-like lectin 5;Siglec-5;CD33 antigen-like 2;Obesity-binding protein 2;OB-BP2;OB-binding protein 2;CD170;SIGLEC14;Sialic acid-binding Ig-like lectin 14;Siglec-14
Organism-1
Human
基因ID-1
8778
SwissProt-1
O15389;Q08ET2
Organism-2
Mouse
SwissProt-2
Q920G3
背景
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012],
细胞定位
Membrane; Single-pass type I membrane protein.





