FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PEPCK-C
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
65kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human PCK1. AA range:491-540
特异性
PEPCK-C Polyclonal Antibody detects endogenous levels of PEPCK-C protein.
基因名称
PCK1
蛋白名称
Phosphoenolpyruvate carboxykinase cytosolic [GTP]
别名
PCK1;PEPCK1;Phosphoenolpyruvate carboxykinase, cytosolic [GTP];PEPCK-C;Phosphoenolpyruvate carboxylase
Organism-1
Human
基因ID-1
5105
SwissProt-1
P35558
Organism-2
Mouse
基因ID-2
18534
SwissProt-2
Q9Z2V4
Organism-3
Rat
基因ID-3
362282
SwissProt-3
P07379
背景
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytosol . Endoplasmic reticulum . Phosphorylation at Ser-90 promotes translocation to the endoplasmic reticulum. .
