- 产品信息
商品描述
靶点-Target
LASP-1
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
28kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human LASP1. AA range:51-100
特异性
LASP-1 Polyclonal Antibody detects endogenous levels of LASP-1 protein.
基因名称
LASP1
蛋白名称
LIM and SH3 domain protein 1
别名
LASP1;MLN50;LIM and SH3 domain protein 1;LASP-1;Metastatic lymph node gene 50 protein;MLN 50
Organism-1
Human
基因ID-1
3927
SwissProt-1
Q14847
Organism-2
Mouse
基因ID-2
16796
SwissProt-2
Q61792
Organism-3
Rat
基因ID-3
29278
SwissProt-3
Q99MZ8
背景
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],
细胞定位
Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Associated with the F-actin rich cortical cytoskeleton. .





