FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SPTLC1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from SPTLC1 . at AA range: 411-460
特异性
SPTLC1 Polyclonal Antibody detects endogenous levels of SPTLC1 protein.
基因名称
SPTLC1
蛋白名称
Serine palmitoyltransferase 1
别名
SPTLC1;LCB1;Serine palmitoyltransferase 1;Long chain base biosynthesis protein 1;LCB 1;Serine-palmitoyl-CoA transferase 1;SPT 1;SPT1
Organism-1
Human
基因ID-1
10558
SwissProt-1
O15269
Organism-2
Mouse
基因ID-2
268656
SwissProt-2
O35704
背景
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013],
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .
