FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DPYD
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
120kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human DPYD. AA range:351-400
特异性
DPYD Polyclonal Antibody detects endogenous levels of DPYD protein.
基因名称
DPYD
蛋白名称
Dihydropyrimidine dehydrogenase [NADP(+)]
别名
DPYD;Dihydropyrimidine dehydrogenase [NADP;+;];DHPDHase;DPD;Dihydrothymine dehydrogenase;Dihydrouracil dehydrogenase
Organism-1
Human
基因ID-1
1806
SwissProt-1
Q12882
Organism-2
Mouse
基因ID-2
99586
SwissProt-2
Q8CHR6
Organism-3
Rat
基因ID-3
81656
SwissProt-3
O89000
背景
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
细胞定位
Cytoplasm.
