CYP11B1/2 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617052
- 产品信息
商品描述
靶点-Target
CYP11B1/2
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
58kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CYP11B1/2. AA range:61-110
特异性
CYP11B1/2 Polyclonal Antibody detects endogenous levels of CYP11B1/2 protein.
基因名称
CYP11B1/CYP11B2
蛋白名称
Cytochrome P450 11B1 mitochondrial/Cytochrome P450 11B2 mitochondrial
别名
CYP11B1;S11BH;Cytochrome P450 11B1, mitochondrial;CYPXIB1;Cytochrome P-450c11;Cytochrome P450C11;Steroid 11-beta-hydroxylase;CYP11B2;Cytochrome P450 11B2, mitochondrial;Aldosterone synthase;ALDOS;Aldosterone-synthesizing enzyme;CYPXIB2;Cytochrome P-450Aldo;Cytochrome P-450C18;Steroid 18-hydroxylase
Organism-1
Human
基因ID-1
1584
SwissProt-1
P15538
背景
cytochrome P450 family 11 subfamily B member 1(CYP11B1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein .





