Neuregulin-2 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617044
- 产品信息
商品描述
靶点-Target
Neuregulin-2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
90kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human NRG2. AA range:361-410
特异性
Neuregulin-2 Polyclonal Antibody detects endogenous levels of Neuregulin-2 protein.
基因名称
NRG2
蛋白名称
Pro-neuregulin-2 membrane-bound isoform
别名
NRG2;NTAK;Pro-neuregulin-2, membrane-bound isoform;Pro-NRG2
Organism-1
Human
基因ID-1
9542
SwissProt-1
O14511
Organism-2
Mouse
SwissProt-2
P56974
Organism-3
Rat
基因ID-3
432361
SwissProt-3
O35569
背景
This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010],
细胞定位
[Pro-neuregulin-2, membrane-bound isoform]: Cell membrane ; Single-pass type I membrane protein . Does not seem to be active. .; [Neuregulin-2]: Secreted .





