Neuregulin-2 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617044

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商品描述
  • 靶点-Target

    Neuregulin-2

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    90kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human NRG2. AA range:361-410

  • 特异性

    Neuregulin-2 Polyclonal Antibody detects endogenous levels of Neuregulin-2 protein.

  • 基因名称

    NRG2

  • 蛋白名称

    Pro-neuregulin-2 membrane-bound isoform

  • 别名

    NRG2;NTAK;Pro-neuregulin-2, membrane-bound isoform;Pro-NRG2

  • Organism-1

    Human

  • 基因ID-1

    9542

  • SwissProt-1

    O14511

  • Organism-2

    Mouse

  • SwissProt-2

    P56974

  • Organism-3

    Rat

  • 基因ID-3

    432361

  • SwissProt-3

    O35569

  • 背景

    This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010],

  • 细胞定位

    [Pro-neuregulin-2, membrane-bound isoform]: Cell membrane ; Single-pass type I membrane protein . Does not seem to be active. .; [Neuregulin-2]: Secreted .