Glypican-3 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617035
- 产品信息
商品描述
靶点-Target
Glypican-3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human GPC3. AA range:461-510
特异性
Glypican-3 Polyclonal Antibody detects endogenous levels of Glypican-3 protein.
基因名称
GPC3
蛋白名称
Glypican-3
别名
GPC3;OCI5;Glypican-3;GTR2-2;Intestinal protein OCI-5;MXR7
Organism-1
Human
基因ID-1
2719
SwissProt-1
P51654
Organism-2
Mouse
基因ID-2
14734
SwissProt-2
Q8CFZ4
Organism-3
Rat
基因ID-3
25236
SwissProt-3
P13265
背景
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side .





