FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ASIC3
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
58kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human ASIC3. AA range:191-240
特异性
ASIC3 Polyclonal Antibody detects endogenous levels of ASIC3 protein.
基因名称
ASIC3
蛋白名称
Acid-sensing ion channel 3
别名
ASIC3;ACCN3;SLNAC1;TNAC1;Acid-sensing ion channel 3;ASIC3;hASIC3;Amiloride-sensitive cation channel 3;Neuronal amiloride-sensitive cation channel 3;Testis sodium channel 1;hTNaC1
Organism-1
Human
基因ID-1
9311
SwissProt-1
Q9UHC3
Organism-2
Mouse
SwissProt-2
Q6X1Y6
背景
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012],
细胞定位
Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4. In part cytoplasmic in cochlea cells (By similarity). .
